[Pandemic influenza A/H1N1 2009 : Challenge for intensive care medicine].
Identifieur interne : 000312 ( Main/Exploration ); précédent : 000311; suivant : 000313[Pandemic influenza A/H1N1 2009 : Challenge for intensive care medicine].
Auteurs : M A Bürkle [Allemagne] ; L. Frey ; B. ZwisslerSource :
- Der Anaesthesist [ 1432-055X ] ; 2010.
Descripteurs français
- KwdFr :
- Allemagne (épidémiologie), Excrétion virale, Grippe humaine (), Grippe humaine (diagnostic), Grippe humaine (virologie), Grippe humaine (épidémiologie), Hospitalisation, Humains, Hygiène, Oxygénation extracorporelle sur oxygénateur à membrane, Pandémies, RT-PCR, Soins de réanimation, Sous-type H1N1 du virus de la grippe A (pathogénicité), Unités de soins intensifs.
- MESH :
- diagnostic : Grippe humaine.
- pathogénicité : Sous-type H1N1 du virus de la grippe A.
- virologie : Grippe humaine.
- épidémiologie : Allemagne, Grippe humaine.
- Excrétion virale, Grippe humaine, Hospitalisation, Humains, Hygiène, Oxygénation extracorporelle sur oxygénateur à membrane, Pandémies, RT-PCR, Soins de réanimation, Unités de soins intensifs.
- Wicri :
- geographic : Allemagne.
English descriptors
- KwdEn :
- Critical Care, Extracorporeal Membrane Oxygenation, Germany (epidemiology), Hospitalization, Humans, Hygiene, Influenza A Virus, H1N1 Subtype (pathogenicity), Influenza, Human (complications), Influenza, Human (diagnosis), Influenza, Human (epidemiology), Influenza, Human (prevention & control), Influenza, Human (virology), Intensive Care Units, Pandemics, Reverse Transcriptase Polymerase Chain Reaction, Virus Shedding.
- MESH :
- geographic , epidemiology : Germany.
- complications : Influenza, Human.
- diagnosis : Influenza, Human.
- epidemiology : Influenza, Human.
- pathogenicity : Influenza A Virus, H1N1 Subtype.
- prevention & control : Influenza, Human.
- virology : Influenza, Human.
- Critical Care, Extracorporeal Membrane Oxygenation, Hospitalization, Humans, Hygiene, Intensive Care Units, Pandemics, Reverse Transcriptase Polymerase Chain Reaction, Virus Shedding.
Abstract
The novel pandemic influenza A/H1N1v has also led to a rapid increase in the number of new cases in Germany. In the majority of patients the disease has taken a mild clinical course. However, in isolated cases severe complications requiring hospitalization or intensive care treatment have occurred. Most of the current recommendations refer to outpatients or mild diseases and are not always suitable and practicable for the management of a life-threatening influenza A/H1N1v infection in an intensive care setting. The aim of this review is to present a reliable diagnostic and therapeutic approach for critically ill patients, considering the current literature, case-based experiences from our own intensive care unit and including relevant recommendations of public health authorities. Initial measures regarding therapeutic, diagnostic and isolation precautions arise from past medical history, current anamnesis and characteristic symptoms and their progression. Patients suspected of having acquired an influenza A/H1N1v infection should be isolated. Early laboratory diagnosis of A/H1N1v infection ideally utilizes the reverse transcriptase polymerase chain reaction (RT-PCR) as the most sensitive diagnostic method. Emerging evidence suggests that incidence and severity of life-threatening influenza A/H1N1v infection increase with several risk factors (e.g. pregnancy, immunosuppression, obesity). Treatment decisions should not be delayed to await laboratory confirmation in these patients as early initiation of antiviral therapy is recommended. Elements of supportive care depend on the presentation of complications and secondary organ failure. If rapidly progressive lung dysfunction occurs, refractory to routine mechanical ventilation, early reporting to centers experienced in the use of extracorporeal membrane oxygenation (ECMO) should be established.
DOI: 10.1007/s00101-009-1667-0
PubMed: 20107944
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
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In the majority of patients the disease has taken a mild clinical course. However, in isolated cases severe complications requiring hospitalization or intensive care treatment have occurred. Most of the current recommendations refer to outpatients or mild diseases and are not always suitable and practicable for the management of a life-threatening influenza A/H1N1v infection in an intensive care setting. The aim of this review is to present a reliable diagnostic and therapeutic approach for critically ill patients, considering the current literature, case-based experiences from our own intensive care unit and including relevant recommendations of public health authorities. Initial measures regarding therapeutic, diagnostic and isolation precautions arise from past medical history, current anamnesis and characteristic symptoms and their progression. Patients suspected of having acquired an influenza A/H1N1v infection should be isolated. Early laboratory diagnosis of A/H1N1v infection ideally utilizes the reverse transcriptase polymerase chain reaction (RT-PCR) as the most sensitive diagnostic method. Emerging evidence suggests that incidence and severity of life-threatening influenza A/H1N1v infection increase with several risk factors (e.g. pregnancy, immunosuppression, obesity). Treatment decisions should not be delayed to await laboratory confirmation in these patients as early initiation of antiviral therapy is recommended. Elements of supportive care depend on the presentation of complications and secondary organ failure. If rapidly progressive lung dysfunction occurs, refractory to routine mechanical ventilation, early reporting to centers experienced in the use of extracorporeal membrane oxygenation (ECMO) should be established.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">20107944</PMID><DateCompleted><Year>2011</Year><Month>06</Month><Day>21</Day></DateCompleted><DateRevised><Year>2020</Year><Month>03</Month><Day>27</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1432-055X</ISSN><JournalIssue CitedMedium="Internet"><Volume>59</Volume><Issue>1</Issue><PubDate><Year>2010</Year><Month>Jan</Month></PubDate></JournalIssue><Title>Der Anaesthesist</Title><ISOAbbreviation>Anaesthesist</ISOAbbreviation></Journal><ArticleTitle>[Pandemic influenza A/H1N1 2009 : Challenge for intensive care medicine].</ArticleTitle><Pagination><MedlinePgn>11-22</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1007/s00101-009-1667-0</ELocationID><Abstract><AbstractText>The novel pandemic influenza A/H1N1v has also led to a rapid increase in the number of new cases in Germany. In the majority of patients the disease has taken a mild clinical course. However, in isolated cases severe complications requiring hospitalization or intensive care treatment have occurred. Most of the current recommendations refer to outpatients or mild diseases and are not always suitable and practicable for the management of a life-threatening influenza A/H1N1v infection in an intensive care setting. The aim of this review is to present a reliable diagnostic and therapeutic approach for critically ill patients, considering the current literature, case-based experiences from our own intensive care unit and including relevant recommendations of public health authorities. Initial measures regarding therapeutic, diagnostic and isolation precautions arise from past medical history, current anamnesis and characteristic symptoms and their progression. Patients suspected of having acquired an influenza A/H1N1v infection should be isolated. Early laboratory diagnosis of A/H1N1v infection ideally utilizes the reverse transcriptase polymerase chain reaction (RT-PCR) as the most sensitive diagnostic method. Emerging evidence suggests that incidence and severity of life-threatening influenza A/H1N1v infection increase with several risk factors (e.g. pregnancy, immunosuppression, obesity). Treatment decisions should not be delayed to await laboratory confirmation in these patients as early initiation of antiviral therapy is recommended. Elements of supportive care depend on the presentation of complications and secondary organ failure. If rapidly progressive lung dysfunction occurs, refractory to routine mechanical ventilation, early reporting to centers experienced in the use of extracorporeal membrane oxygenation (ECMO) should be established.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Bürkle</LastName><ForeName>M A</ForeName><Initials>MA</Initials><AffiliationInfo><Affiliation>Klinik für Anaesthesiologie, Klinikum der Ludwig-Maximilians-Universität München, Campus Grosshadern, Deutschland. martin.buerkle@med.uni-muenchen.de</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Frey</LastName><ForeName>L</ForeName><Initials>L</Initials></Author><Author ValidYN="Y"><LastName>Zwissler</LastName><ForeName>B</ForeName><Initials>B</Initials></Author></AuthorList><Language>ger</Language><PublicationTypeList><PublicationType UI="D004740">English Abstract</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D016454">Review</PublicationType></PublicationTypeList><VernacularTitle>Neue Influenza-A/H1N1-2009-Virus-Pandemie : Herausforderung für die Intensivmedizin.</VernacularTitle></Article><MedlineJournalInfo><Country>Germany</Country><MedlineTA>Anaesthesist</MedlineTA><NlmUniqueID>0370525</NlmUniqueID><ISSNLinking>0003-2417</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D003422" MajorTopicYN="Y">Critical Care</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D015199" MajorTopicYN="N">Extracorporeal Membrane Oxygenation</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005858" MajorTopicYN="N" Type="Geographic">Germany</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006760" MajorTopicYN="N">Hospitalization</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" 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sortKey="Frey, L" sort="Frey, L" uniqKey="Frey L" first="L" last="Frey">L. Frey</name><name sortKey="Zwissler, B" sort="Zwissler, B" uniqKey="Zwissler B" first="B" last="Zwissler">B. Zwissler</name></noCountry><country name="Allemagne"><region name="Bavière"><name sortKey="Burkle, M A" sort="Burkle, M A" uniqKey="Burkle M" first="M A" last="Bürkle">M A Bürkle</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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